Asymmetric epigenetic modification and homoeolog expression bias in the establishment and evolution of allopolyploid <i>Brassica napus</i>

This study explores how allopolyploidization reshapes the biased expression and asymmetric epigenetic modification of homoeologous gene pairs, examines regulation types basis bias. We analyzed four modifications (DNA methylation, H3K4me3, H3K27me3 H3K27ac) 29 976 pairs in resynthesized, natural allopolyploid Brassica napus an silico ‘hybrid’. comprehensively elucidated expression, generational transmission characteristics these B. napus. cis/trans effects homoeolog There was a significant positive correlation between two active histone expression. revealed that parental legacy dominant principle remodeling bias napus, further clarified this depends on whether there were differences expression/epigenetic parents/progenitors. The maternal genome resynthesized phenomenon attenuated Furthermore, cis rather than trans when potentially affected